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The chemistry of 2 H ‐1,3‐benzoxazine‐2,4‐(1 H )dione (isatoic anhydride). 8 . A one step synthesis of the quinindoline ring system and related compounds
Author(s) -
Coppola Gary M.
Publication year - 1980
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570170831
Subject(s) - chemistry , carbanion , ring (chemistry) , oxindole , tricyclic , organic chemistry , medicinal chemistry , catalysis
The reaction between N ‐substituted isatoic anhydrides and the carbanion generated from 3‐methylthio‐oxindole to produce the quinindoline ring skeleton is discussed. Analogous reactions of azaisatoic anhydride 6 and tricyclic anhydride 8 produces the 4‐aza analog 7 and pentacycle 9 . Some spectral data is also described.
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