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Derivatives of perhydrofuro[2,3‐ c ]pyridin‐2‐one
Author(s) -
Borne Ronald F.,
AboulEnein Hassan Y.
Publication year - 1980
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570170753
Subject(s) - chemistry , ring (chemistry) , pilocarpine , combinatorial chemistry , stereochemistry , organic chemistry , epilepsy , neuroscience , biology
Synthetic approaches to the preparation of perhydrofuro[2,3‐ c ]pyridin‐2‐one derivatives as analogs of pilocarpine are reported. Derivatives of the desired ring system were obtained from iodolactonization of the appropriate tetrahydropyridyl esters.