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Reactions of ethyl cinnamates with arylacetamides
Author(s) -
Shandala Mowafak Y.,
AlKhashab AbdulIlah Y.,
Afzal M.,
Ahmad Shakir S.
Publication year - 1980
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570170752
Subject(s) - cinnamates , chemistry , condensation , claisen condensation , organic chemistry , medicinal chemistry , catalysis , physics , thermodynamics
Reactions of ethyl cinnamates with arylacetamides gave the corresponding 2,6‐diketo‐3,4‐diarylpiperidine ( 1a‐o ) in addition to the corresponding cinnamides ( 2a‐o ) and arylacetates ( 3a‐o ). The latter two are formed from the intermediates of the Claisen condensation of the reactants. On the other hand and contrary to the above results, condensation of p ‐methoxycinnamate with arylacetamides gave only p ‐methoxycinnamide in quantitative yields with the corresponding arylacetates.

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