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The synthesis of 3 H ‐pyrazol‐3‐one derivatives containing a 9 H ‐xanthene ring
Author(s) -
Okabayashi Ichizo
Publication year - 1980
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570170643
Subject(s) - xanthene , chemistry , phenylhydrazine , ring (chemistry) , medicinal chemistry , condensation , stereochemistry , organic chemistry , physics , thermodynamics
2,4‐Dihydro‐5‐methyl‐2‐phenyl‐4‐(9 H ‐xanthen‐9‐yl)‐3 H ‐pyrazol‐3‐one ( 3 ) was prepared by the condensation of phenylhydrazine and ethyl α‐acetyl‐9 H ‐xanthene‐9‐acetate ( 2 ), or 9 H ‐xanthen‐9‐ol ( 1 ) and 2,4‐dihydro‐5‐methyl‐2‐phenyl‐3 H ‐pyrazol‐3‐one ( 4 ). 5‐Amino‐2,4‐dihydro‐2‐phenyl‐4‐(9 H ‐xanthen‐9‐yl)‐3 H ‐pyrazol‐3‐one ( 6 ) was obtained by the condensation of 1 and 5‐amino‐2,4‐dihydro‐2‐phenyl‐3 H ‐pyrazol‐3‐one ( 5 ).
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