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Convenient total synthesis of ( dl )‐quebrachamine
Author(s) -
Giri Venkatachalam S.,
Ali Esahak,
Pakrashi Satyesh C.
Publication year - 1980
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570170563
Subject(s) - chemistry , total synthesis , lactam , reduction (mathematics) , stereochemistry , organic chemistry , mathematics , geometry
Racemic quebrachamine ( 1 ) has been synthesised from 2‐hydroxytryptamine and dimethyl 4‐ethyl‐4‐formylpimelate through 1,2‐dehydroaspidospermidine ( 8 ), obtained by selective reduction of the carbonyl function of lactam 3.