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Synthesis of 2,2a,4,5‐tetraazabenz[ cd ] azulene derivatives
Author(s) -
Imafuku Kimiaki,
Sumio Miyuki,
Matsumura Hisashi
Publication year - 1980
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570170540
Subject(s) - azulene , chemistry , hydrazone , medicinal chemistry , formate , organic chemistry , catalysis
3‐Methyl‐1,8‐dihydrocycloheptapyrazol‐8‐one hydrazone ( 5 ) reacted with triethyl ortho‐formate, orthoacetate and orthopropionate to afford 2,2a,4,5‐tetraazabenz[ cd ]azulene derivatives ( 7a‐c ). 3‐Methyl‐ ( 7b ) and 3‐phenyl‐substituted compounds ( 7d ) were also obtained by the reactions of 5 with acetyl and benzoyl chlorides, respectively.