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Synthesis of 2‐amino‐3‐hydroxy‐ and of 2,3‐diamino‐3 H ‐1,4‐benzodiazepines
Author(s) -
Gatta Franco,
Del Giudice Maria Rosaria,
Di Simone Luciano,
Settimj Guido
Publication year - 1980
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570170504
Subject(s) - chemistry , stereochemistry , medicinal chemistry
A new synthesis of 7‐chloro‐2,3‐diamino‐5‐phenyl‐3 H ‐1,4‐benzodiazepines is described, which allows for the preparation of compounds bearing the same or different substituents at the 2 and 3 positions, starting from 2‐amino‐7‐chloro‐3‐hydroxy‐5‐phenyl‐3 H ‐1,4‐benzodiazepines.
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