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3,3‐Dinitrobutyl‐1,2,4‐oxadiazoles
Author(s) -
Bjorklund Mark D.,
Coburn Michael D.
Publication year - 1980
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570170443
Subject(s) - chemistry , oxadiazole , yield (engineering) , aryl , chloride , organic chemistry , medicinal chemistry , combinatorial chemistry , alkyl , materials science , metallurgy
The syntheses of 3,5‐ bis (3,3‐dinitrobutyl)‐1,2,4‐oxadiazole and a series of 3‐aryl‐5‐(3,3‐dinitrobutyl)‐1,2,4‐oxadiazoles were accomplished by treating 4,4‐dinitropentanoyl chloride with the appropriate amidoximes to yield the intermediate O ‐(4,4‐dinitropentanoyl)amidoximes, which were dehydrated to the 1,2,4‐oxadiazoles.