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Heteroatomic chains and their products of cyclisation. IV. t ‐butyl‐2‐phthalimido‐2‐(3,6‐dihydro‐1,3‐2 H ‐thiazine‐2‐yliden)‐acetates substituted in position 5 by a functional group
Author(s) -
Duguay Guy,
Guémas JeanPierre,
Meslin JeanClaude,
Pradère JeanPaul,
Reliquet Françoise,
Reliquet Alain,
TeaGokou Célestin,
Quiniou Hervé,
Rabiller Claude
Publication year - 1980
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570170428
Subject(s) - chemistry , thiazine , stereochemistry , bicyclic molecule , medicinal chemistry
Substituted N ′‐thioacetylformamidines, readily enthiolized, exist in fact in the form of zwitterions 8 with the transfer of the mobile hydrogen on the nitrogen N ′. These zwitterions under (4 + 2) cyclocondensation with dienophiles. The dihydrothiazines formed ( 10 ) are possible interesting intermediates in the synthesis of cephems and cephalosporin analogs.