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A benzofuran analog of chloramphenicol
Author(s) -
Bevinakatti Hanamanthsa S.,
Badiger Virupax V.
Publication year - 1980
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570170342
Subject(s) - chemistry , benzofuran , propane , diol , chloramphenicol , mass spectrum , organic chemistry , stereochemistry , medicinal chemistry , mass spectrometry , chromatography , antibiotics , biochemistry
Preparation of dl‐threo ‐2‐dichloroacetamido‐1‐(2‐benzofuranyl)propane‐1,3‐diol (VI), adopting the method of Sorm, et al , has been described. The structures of the final compound (VI) as well as of the two precursors (V and IV) have been confirmed by ir, nmr and mass spectral studies.