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Synthesis and absolute configuration of 3‐ethyl and 3‐ n ‐propylpyrrolidine
Author(s) -
Bettoni Giancarlo,
Cellucci Carla,
Berardi Francesco
Publication year - 1980
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570170339
Subject(s) - chemistry , absolute configuration , racemization , specific rotation , optical rotation , optically active , absolute (philosophy) , succinic acid , stereochemistry , combinatorial chemistry , organic chemistry , philosophy , epistemology
Optically active 3‐ethyl and 3‐ n ‐propylpyrrolidine were prepared by two independent routes from their corresponding succinic acids and the absolute configurations were assigned. Maximum optical rotation was also established through evaluation of the degree of racemization of the products obtained via both synthetic routes.