Premium
Novel synthesis of the pharmacologically important 1‐substituted‐6‐phenyl‐4 H ‐ s ‐triazolo[4,3‐ a ][1,4]benzodiazepines
Author(s) -
Hester Jackson B.
Publication year - 1980
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570170331
Subject(s) - chemistry , benzodiazepine , ring (chemistry) , stereochemistry , benzazepines , combinatorial chemistry , organic chemistry , biochemistry , receptor
Several 6‐phenyl‐4 H ‐ s ‐triazolo[4,3‐ a ][1,4]benzodiazepines have useful biological activity both in experimental animals and in man. This manuscript describes a novel synthesis of these compounds from intermediates that do not have a pre‐formed benzodiazepine ring system.