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Synthesis of 4,7‐dimethoxyindoles bearing substituents at the c‐5 and c‐6 positions and studies on their demethylation products
Author(s) -
Malesani Giorgio,
Galiano Fabio,
Ferlin Maria Grazia,
Masiero Sergio
Publication year - 1980
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570170329
Subject(s) - chemistry , demethylation , aluminium chloride , benzene , bearing (navigation) , chloride , medicinal chemistry , stereochemistry , aluminium , organic chemistry , biochemistry , gene expression , cartography , dna methylation , gene , geography
Syntheses of some 4,7‐dimethoxyindoles bearing methyl, amino or acetamido groups at the C‐5 and C‐6 positions were investigated. The presence of these substituents made possible the isolation of the corresponding 4,7‐dihydroxyindole derivatives obtained by long reflux with aluminium chloride in benzene solution.