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Synthesis in the diazasteroid group. XII Syntheses of the 10,17‐diazasteroid and 10‐aza‐17‐thiasteroid systems
Author(s) -
Takahata Hiroki,
Hara Misao,
Tomiguchi Akira,
Yamazaki Takao,
Castle Raymond N.
Publication year - 1980
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570170241
Subject(s) - chemistry , piperidine , raney nickel , group (periodic table) , flue gas desulfurization , organic chemistry , medicinal chemistry , stereochemistry , catalysis
Upon desulfurization with Raney Ni, the condensed heterocycles 2a,b prepared by cyclization from β‐ketosulfoxides 1a,b gave β‐ketones 3a,b , which were condensed with 2‐carbethoxymethyl‐piperidine 4 to afford the 10,17‐diazasteroid 6 and the 10‐aza‐17‐thiasteroid 7 , respectively.
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