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New heterocyclic ring systems. XI. Azadithiasteroid analogues
Author(s) -
Fravolini A.,
Schiaffella F.,
Brunelli C.,
Cecchetti V.
Publication year - 1980
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570170126
Subject(s) - chemistry , hydrazine (antidepressant) , ring (chemistry) , amine gas treating , glycine , medicinal chemistry , stereochemistry , organic chemistry , amino acid , biochemistry , chromatography
Synthesis of the title compounds has been achieved starting from 4‐oxo‐3,4‐dihydro‐2 H ,5 H ‐thiopyrano[3,2‐ c ][1]benzothiopyran 6,6‐dioxide (III), which was converted to glyoxylate (IV), β‐ketoester (V), difluoride complex (VII) and β‐diketone (XII) gave with hydrazine, hydroxyl‐amine and glycine ethyl ester several azadithiasteroid analogues.