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Alkylating nucleosides. 3 . The reaction of 3,5‐dimethylpyrazole nucleosides with N ‐bromosuccinimide
Journal Of Heterocyclic ChemistryPeer ReviewedGarcia Lópe M. Teresa +21980Journals
Bromination of 3,5‐dimethylpyrazole nucleosides with N ‐bromosuccinimide gave the corresponding 4‐bromo‐3,5‐dimethylpyrazole, 3‐methyl‐5‐(bromomethyl)pyrazole and 4‐bromo‐3‐methyl‐5‐(bromomethyl)pyrazole nucleosides. Structural assignments were made on basis of analytical and 1 H nmr spectral data. All of the bromomethylpyrazole nucleosides described showed cytostatic activity against HeLa cell sultures.
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