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Studies on sulphur heterocycles. Reactions of 6,7‐dihydrobenzo[ b ]thiophen‐4(5 H )one derivatives and their conversion to 7‐substituted thieno[2,3‐ h ][1]benzopyran‐8‐ones
Author(s) -
Asprou Chris M.,
Brunskill John S. A.,
Jeffrey Howard,
De Asish
Publication year - 1980
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570170118
Subject(s) - chemistry , sulfur , medicinal chemistry , reaction conditions , organic chemistry , stereochemistry , catalysis
Cyclization of γ‐(2‐thienyl)butryic acid with acid anhydrides gives 2‐acyl derivatives as well as the expected 6,7‐dihydrobenzo[ b ]thiophen‐4(5 H )one. Several reactions of these ketones have been studied including their conversion to 0,0‐diethyl thiophosphonohydrazones. 7‐Substituted thieno[2,3‐ h ][1]benzopyran‐8‐ones have been prepared via 4‐hydroxybenzo[ b ]thiophen‐5‐carbaldehydes.