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Indole related compounds. Reaction of 1‐protected‐indoles with pyridine substrates
Author(s) -
Caixach J.,
Capell R.,
Galvez C.,
Gonzalez A.,
Roca N.
Publication year - 1979
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570160821
Subject(s) - chemistry , pyridine , pyridinium , indole test , salt (chemistry) , organic chemistry , medicinal chemistry , combinatorial chemistry
The products resulting from the reactions of 1‐benzenesulfonyl‐2‐lithioindole and 2‐lithio‐1‐methylindole with different pyridine substrates (pyridine, 1‐methoxy‐pyridinium salt and 2‐bromopyridine) have been studied. The use of lithiocyclohexylisopyropylamide as a lithiating agent of indoles has been investigated. The preparation of four of the possible benzenesulfonyl derivatives of 2‐(2′ ‐pyridyl)indole is described.