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Carbon‐13 and proton magnetic resonance spectra of 2,4‐disubstituted 3,3‐diphenyltetrahydrofurans derived from isomethadone and isomethadol
Author(s) -
Williams David A.,
Makriyannis Alexandros
Publication year - 1979
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570160626
Subject(s) - chemistry , diastereomer , proton magnetic resonance , chemical shift , coupling constant , spectral line , proton , ammonium , derivative (finance) , pyrolysis , carbon fibers , carbon 13 nmr , nmr spectra database , medicinal chemistry , nuclear magnetic resonance , stereochemistry , organic chemistry , physics , materials science , particle physics , astronomy , quantum mechanics , composite number , financial economics , economics , composite material
Proton and carbon‐13 nmr spectra for cis‐ and trans ‐2‐ethyl‐3,3‐diphenyl‐4‐methyltetrahydrofurans and 2‐ethylidene‐3,3‐diphenyl‐4‐methyltetrahydrofuran, derived from the pyrolysis of the quaternary ammonium salts of the diastereomeric isomethadols and isomethadone, respectively, are reported. 1 H and 13 C chemical shifts and 1 H‐ 1 H coupling constants have been assigned in each case. The isomeric teterahydrofurans have been analyzed in terms of a half‐chair conformation, and an envelope conformation for the ethylidene derivative.