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Synthesis of some new fluorine‐containing 5‐amino‐1,3‐disubstituted pyrazoles and 1 H ‐pyrazolo[3,4‐ b ]pyridines
Author(s) -
Joshi Krishna C.,
Pathak Vijai N.,
Garg Urmila
Publication year - 1979
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570160611
Subject(s) - chemistry , acetic acid , fluorine , condensation , spectral analysis , medicinal chemistry , stereochemistry , organic chemistry , spectroscopy , thermodynamics , quantum mechanics , physics
Nine new fluorine containing 5‐amino‐1,3‐disubstituted pyrazoles have been synthesized and characterized by spectral studies. Condensation reactions of these 5‐amino‐1,3‐disubstituted pyrazoles with fluorinated 1,3‐diketones in the presence of glacial acetic acid have been studied and the structures of the resulting 1 H ‐pyrazolo[3,4‐ b ]pyridines have been confirmed by ir, pmr and 19 F nmr spectral studies.