Premium
Reactions of β‐heteroatom substituted α,β‐unsaturated ketones with dimethylsulfonium methylide
Author(s) -
Nishio Takehiko,
Sugawara Mitsuko,
Omote Yoshimori
Publication year - 1979
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570160443
Subject(s) - chemistry , furan , heteroatom , pyrrole , methylene , ketone , organic chemistry , medicinal chemistry , alkoxy group , ring (chemistry) , alkyl
β‐Alkoxy‐ and β‐alkylthio α,β‐unsaturated ketones react with dimethylsulfonium methylide (DMSM) to give a furan, while β‐anilino α,β‐unsaturated ketones give the pyrrole. β,β‐Bis(alkylthio) α,β‐unsaturated ketones react with DMSM to afford the methylene inserted products, λ,λ‐bis(alkylthio) β,λ‐unsaturated ketones.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom