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Reaction of tetraoxopyrrolo [2,3‐ d ] pyrimidines, isatin analogues, with o ‐phenylenediamine
Author(s) -
Bernier JeanLuc,
Hénichart JeanPierre
Publication year - 1979
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570160421
Subject(s) - chemistry , isatin , o phenylenediamine , condensation , pyrimidine , condensation reaction , p phenylenediamine , mass spectrum , medicinal chemistry , stereochemistry , organic chemistry , combinatorial chemistry , ion , physics , thermodynamics , catalysis
In the course of general studies on new antitumor tetracyclic intercalating agents, the condensation of o ‐phenylenediamine with two new tetraoxopyrrolo[2,3‐ d ]pyrimidine derivatives has been carried out. The structure of the reaction products as arylketimines has been elucidated and mass spectral fragmentations are discussed.