Polyazasteroids II. . 1,2,4‐Triazolol[3′,4′:2,3]pyrimido[4,5‐ c ]quinolin‐ 11(12 H )ones, imidazo[2′,1′:2,3]pyrimido[4,5‐ c ]quinolin‐11(12 H )ones and 2,3‐dihydroimidazo[2′,1′:2,3] pyrimido[4,5‐ c ]quinolin‐11(12 H )ones | Zendy

Lalezari I. | Zendy; SadeghiMilani S. | Zendy

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Polyazasteroids II. . 1,2,4‐Triazolol[3′,4′:2,3]pyrimido[4,5‐ c ]quinolin‐ 11(12 H )ones, imidazo[2′,1′:2,3]pyrimido[4,5‐ c ]quinolin‐11(12 H )ones and 2,3‐dihydroimidazo[2′,1′:2,3] pyrimido[4,5‐ c ]quinolin‐11(12 H )ones

Author(s) -

Lalezari I.,

SadeghiMilani S.

Publication year - 1979

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570160419

Subject(s) - chemistry , quinoline , nitrous acid , stereochemistry , medicinal chemistry , organic chemistry

Starting with 2‐substituted quinoline‐3,4‐dicarboxylic acids, a series of substituted 1,2,3,4‐tetrahydropyrimido[4,5‐ c ]quinolinone‐3‐thiones were obtained. The latter compounds were converted to the three novel polyazasteroid series: 1,2,4‐Triazolo[3′,4′:2,3]pyrimido[4,5‐ c ]‐quinolin‐11(12 H )ones, imidazo[2′,1′:2,3]pyrimido[4,5 c ]quinolin‐11(12 H )ones and 2,3‐dihydroimidazo[2′,1′:2,3]pyrimido[4,5‐ c ]quinolin‐11(12 H )ones. The intermediate 3‐hydrazino‐1,2‐dihydropyrimido[4,5‐ c ]quinolinones and nitrous acid gave the 3‐azido derivatives rather than the tetrazolo compounds.

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