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Sulphur heterocycles from thiodiacetonitrile and sulphonyldiacetonitrilc
Author(s) -
Crombie D. A.,
Kiely J. R.,
Ryan C. J.
Publication year - 1979
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570160237
Subject(s) - chemistry , sulfur , organic chemistry , medicinal chemistry
Thiodiacetonitrile reacted with α‐diketones to form 5‐cyano‐2‐thiophenecarboxamides and with α‐keto esters to give 3‐hydroxy‐2,5‐thiophenedicarbonitriles. Sulphonyldiacclonitrile condensed with α,β‐unsaturated ketones to give 6‐cyano‐3,4‐dihydro‐1,1‐dioxo‐2 H ‐thiopyran‐2‐carboxamides.
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