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Heterocyclic. Compounds. X. Bis(2‐chloroethyl)amino substituted β‐lactams as potential antineoplastic agents
Author(s) -
Manilas M. S.,
Min S. G. A.,
Glazer R. D.
Publication year - 1979
Publication title -
journal of heterocyclic chemistry
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570160217
Subject(s) - chemistry , stereochemistry , lactam , combinatorial chemistry
The synthesis of variously substituted β‐lactams carrying a bis(2‐chloroethyl) amino group is described. Some of these compounds show mild antitumor activity and low toxicity.