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A novel synthesis of the benzo[ F ]quinazoline ring system
Author(s) -
Delia Thomas J.,
Munslow William D.
Publication year - 1979
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570160208
Subject(s) - chemistry , quinazoline , ring (chemistry) , pyrimidine , ketone , uracil , stereochemistry , combinatorial chemistry , organic chemistry , dna , biochemistry
An approach to the synthesis of the benzo[ f ]quinazoline ring system using a preformed pyrimidine is described. A facile cyclization of a ketone function into the 5‐position of uracil is the key step in this sequence.