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Benzo[ B ]thiophene derivatives XXIV. Oxidation of o ‐dihydroxybenzo[ b ]thiophene methyl ethers
Author(s) -
Campaigne K.,
Homfeld E.
Publication year - 1979
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570160206
Subject(s) - chemistry , thiophene , ceric ammonium nitrate , medicinal chemistry , oxidative phosphorylation , cerium , nitration , organic chemistry , polymer , biochemistry , grafting
The attempted oxidative demethylation of a series of o‐dihydroxybenzo[ b ]thiophene methyl ethers with cerium (IV), argentic oxide, periodale and thallate usually led to intractable mixtures. However, in one ease, use of ceric ammonium nitrate resulted in nitration of the benzo[ b ]‐thiophene ring. In another example, treatment with aqueous periodate or thallate resulted in oxidative hydroxylation of benzo[ b ]thiophene.