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Reactions with cyclic amidines II. The behaviour of cyclic amidines toward ethoxycarbonyl and aroyl isothiocyanates
Author(s) -
Elnagdi Mohamed Hilmy,
Fahmy Sherif Mahmoud,
Elmoghayar Mohamed Rifaat Hamza,
Kandeel Ezzat Mohamed
Publication year - 1979
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570160114
Subject(s) - chemistry , ring (chemistry) , thiocyanate , medicinal chemistry , amidine , cyclic amines , stereochemistry , organic chemistry , amine gas treating
The behaviour of the aminopyrazole derivatives 1a‐c, 2‐amino‐4‐phenylthiazole (2) and 2‐amino‐5‐phenyl‐1,3,4‐thiadiazole (3) toward the action of ethoxycarbonyl and benzoyl iso‐thiocyanate is reported. The data clearly demonstrates the dependence of the nature of the products obtained from the reaction of isothiocyanates with cyclic amidines on the nature of the substituents on the heterocyclic ring.