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Polymorphism in the 2‐(4‐morpholinothio) benzothiazole
Author(s) -
Guzman J.,
LargoCabrerizo J.
Publication year - 1978
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570150865
Subject(s) - benzothiazole , chemistry , conformational isomerism , polymorphism (computer science) , crystal structure , flexibility (engineering) , crystallography , stereochemistry , thermodynamics , molecule , organic chemistry , genotype , biochemistry , statistics , physics , mathematics , gene
The existence of two conformational isomers (A and B) with different crystal structures in 2‐(4‐morpholinothio) benzothiazole is shown. The melting temperatures of the two conformers are 345° and 357° K, respectively. The difference between the values of the melting enthalpies and entropies gives an indication of the two isomers flexibility whose proportion depends on the thermal history of the sample.