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Synthesis and reduction of some 1 H ‐2,1,3‐benzothiadiazin‐4(3 H ) one 2,2‐dioxides
Author(s) -
Bancroft Keith C. C.,
Guindi Laila H. Morcos,
Temple Arthur F.
Publication year - 1978
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570150861
Subject(s) - benzothiadiazine , chemistry , anthranilic acid , medicinal chemistry , combinatorial chemistry , organic chemistry , stereochemistry
Several 2,1,3‐benzothiadiazin‐4(3 H ) one 2,2‐dioxides were synthesized as possible sweetening agents by reacting sulfamoyl chloride with various anthranilic acid derivatives. The isolation of 1‐methyl‐4‐methoxy‐2,1,3‐benzothiadiazine 2,2‐dioxide and preparation of 3,4‐dihydro‐2,1,3‐benzothiadiazine 2,2‐dioxide is also reported.