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An improved preparation of tetrahydropyridines from 1‐alkyl‐3‐acylpyridinium salts
Author(s) -
Chevolot L.,
Husson H.P.
Publication year - 1978
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570150855
Subject(s) - chemistry , alkyl , hydrogen phosphate , methanol , sodium , charcoal , phosphate , sodium salt , hydrogen , organic chemistry , nuclear chemistry , inorganic chemistry
The hydrogenation of 1‐alkyl‐3‐acylpyridinium salts in methanol in the presence of 10% palladium‐charcoal/disodium hydrogen phosphate‐sodium dihydrogenphosphate suspension leads to the corresponding tetrahydropyridines. This represents an improvement over the Wenkert method.