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Tetracyclic phenothiazines V . Construction of the azepino[3,2,1‐ kl ] ‐phenothiazine ring system by regioselective ring expansion
Author(s) -
Kim Sun H.,
Martin Arnold R.
Publication year - 1978
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570150854
Subject(s) - chemistry , phenothiazine , solvolysis , ring (chemistry) , regioselectivity , medicinal chemistry , stereochemistry , organic chemistry , catalysis , pharmacology , hydrolysis , medicine
Solvolysis of 1,2‐dihydro‐3‐hydroxy‐3‐( p ‐toluenesolfonyloxymethyl) 3 H ‐pyrido[3,2,1‐ kl ]‐phenothiazine gave 1,2,3,4‐tetrahydroazepino[3,2,1‐ kl ]phenothiazin‐3‐one.