4‐Amino‐6‐hydroxy‐1 H ‐pyrrolo[3,2‐ c ] pyridine (3,7‐dideazaisoguanine) | Zendy

Schneller S. W. | Zendy; Hosmane R. S. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

4‐Amino‐6‐hydroxy‐1 H ‐pyrrolo[3,2‐ c ] pyridine (3,7‐dideazaisoguanine)

Author(s) -

Schneller S. W.,

Hosmane R. S.

Publication year - 1978

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570150853

Subject(s) - chemistry , pyridine , sodium carbonate , aqueous solution , acetic acid , ring (chemistry) , medicinal chemistry , stereochemistry , sodium , organic chemistry

The preparation of 4‐amino‐6‐hydroxy‐1 H ‐pyrrolo[3,2‐ c ]pyridine (3,7‐dideazaisoguanine) ( 1 ) in five steps from 1 H ‐pyrrolo[3,2‐ c ]pyridin‐4,6(5 H ,7 H ) dione (3,7‐dideazaxanthine) ( 2 ) is described. Furthermore, prolonged treatment of 1 with 10% aqueous sodium carbonate solution is reported to lead to ring opening of the pyridine of 1 resulting in 3‐carboxamidopyrrole‐2‐acetic acid ( 3 ).

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research