Reissert compound studies. XXXI. Emetine analogs based on the reaction of the reissert anion with 1,3,4,6,7,11b‐hexahydro‐9, 10‐dimethoxybenzo[ a ] quinolizin‐2‐ones

Reaction of the Reissert anion with the carbonyl group of 1,3,4,6,7,11b‐hexahydro‐9,10‐dimethoxybenzo[ a ]quinolizin‐2‐one and with 3‐ethyl‐1,2,3,4,6,7‐hexahydro‐9,10‐dimethoxy‐11b H ‐benzo[ a ]quinolizin‐2‐carboxaldehyde give emetine analogs. This anion does not react with the carbonyl group of 3‐aIkyl‐1,3,4,6,7,11b‐hexahydro‐9,10‐dimethoxybenzo[ a ]quinolizin‐2‐one but instead gives a rearrangement product and the benzoquinolizinone cyanohydrin.