Premium
Synthesis of 3(2‐ and 4‐Pyridinyl)‐1,3,4‐oxadiazol‐2(3 H )ones
Author(s) -
Giacobbe Thomas J.
Publication year - 1978
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570150728
Subject(s) - chemistry , halo , pyridine , alkoxy group , salt (chemistry) , alkali metal , medicinal chemistry , combinatorial chemistry , organic chemistry , physics , alkyl , quantum mechanics , galaxy
The synthetic objective of preparing halo‐ and halo‐ plus alkoxy‐substituted pyridyloxadiazolones was achieved by allowing an alkali metal salt of an oxadiazolone to displace a leaving group on a halo‐ or halo‐ plus alkoxy‐substituted pyridine, respectively. Other routes failed to give the desired compounds, and they are briefly discussed.