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Derivatives of phenyl‐2,3‐dihydroimidazo[1,2‐ a ]pyridinone
Author(s) -
Magatti Charles V.,
Villani Frank J.
Publication year - 1978
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570150622
Subject(s) - chemistry , acylation , intramolecular force , medicinal chemistry , hydride , condensation , organic chemistry , stereochemistry , catalysis , hydrogen , physics , thermodynamics
The title compounds were prepared by the condensation of a series of β‐keto esters with 2‐benzylimidazoline. A mechanism is proposed wherein the dienamine 4 undergoes an intramolecular acylation with the elimination of ethoxide and subsequent hydride shift.