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1 H Nmr structural analysis of azabicyclospirohydantoins
Author(s) -
Trigo G. G.,
Galvez E.,
Avendaño C.
Publication year - 1978
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570150603
Subject(s) - chemistry , nonane , piperidine , ring (chemistry) , cyclohexane conformation , stereochemistry , alkyl , carbon 13 nmr , carbon atom , group (periodic table) , crystallography , molecule , organic chemistry , hydrogen bond
Abstract Based on the data from 1 H nmr spectra, the structure and spatial configuration of the ahove mentioned hydantoins are established. In the 3‐alkyl‐3‐azabicyelo[3.3.f ]nonane‐9‐spiro‐5′‐hydantoins analyzed, we confirm the chair‐chair configuration and the presence of only one stereoisomer at the spiro carbon atom (with the C 4 ′=() group axial with regard to the piperidine ring). In the 3,7‐dialkyl‐3,7‐diazabieyclo[3.3.1 ]nonane‐9‐spiro‐5′‐hydantoins analyzed, we also confirm the chair‐chair configuration and we calculate the percentage of the two stereoisomers when they exist.