The use of α‐(aryl)‐4‐morpholineacetonitriles (masked acyl anion equivalents) in 1,4‐additions to α,β‐unsaturated esters and nitriles. A versatile synthetic route to 6‐aryl‐3(2 H ) pyridazinones | Zendy

Albright J. D. | Zendy; Mcevoy F. J. | Zendy; Moran Daniel B. | Zendy

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The use of α‐(aryl)‐4‐morpholineacetonitriles (masked acyl anion equivalents) in 1,4‐additions to α,β‐unsaturated esters and nitriles. A versatile synthetic route to 6‐aryl‐3(2 H ) pyridazinones

Author(s) -

Albright J. D.,

Mcevoy F. J.,

Moran Daniel B.

Publication year - 1978

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570150601

Subject(s) - chemistry , acrylonitrile , aryl , ethyl acrylate , acrylate , organic chemistry , methyl acrylate , medicinal chemistry , alkyl , polymer , monomer , copolymer

The use of α‐(substituted‐phenyl)‐4‐morpholineacetonitriles in 1,4‐additions to ethyl acrylate, ethyl crotonate, methyl α‐methylacrylate, acrylonitrile, methylacrylonitrile, crotononitrile and cinnamonitrile was studied. A convenient route to 6‐aryl‐4,5‐dihydro‐3(2 H ) pyridazinones from aryl aldehydes and heterocyclic aldehydes was developed.

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