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Assignment and solvent dependence of the carbon‐13 nuclear magnetic resonance spectrum of nicotine
Author(s) -
Pitner T. Phil,
Seeman Jeffrey I.,
Whidby Jerry F.
Publication year - 1978
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570150412
Subject(s) - chemistry , deuterium , coupling constant , carbon 13 , pyridine , solvent , acetone , nicotine , population , nuclear magnetic resonance , analytical chemistry (journal) , medicinal chemistry , organic chemistry , atomic physics , nuclear physics , physics , demography , particle physics , neuroscience , sociology , biology
The 13 C nmr spectrum of nicotine is assigned in Acetone‐ d 6 , DMSO‐ d 6 , Pyridine‐ d 5 , and deuterium oxide (pD 10.7, 5.4, < 1). Attention is focused on assignment of the closely‐spaced C(2) and C(6) resonances, using selective decoupling, population transfer, and long‐range coupling constant measurements. C(2) resonates at lower field in the organic solvents hut at higher field in deuterium oxide at all pD values investigated.