Premium
Synthesis of 2‐methyl‐3‐(3,5‐diallyl‐4‐hydroxyphenyl)‐4‐quinazolones as possible anticonvulsants
Author(s) -
Rastogi V. K.,
Parmar S. S.,
Singh S. P.,
Akers T. K.
Publication year - 1978
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570150327
Subject(s) - chemistry , anticonvulsant , pentobarbital , medicinal chemistry , pharmacology , epilepsy , neuroscience , medicine , biology
A series of 2‐methyl‐3‐(3,5‐diallyl‐4‐hydroxyphenyl)‐4‐quinazolones were prepared as possible anticonvulsants. All compounds were evaluated for their anticonvulsant activity against pentylene‐tetrazol‐induced seizures and their ability to potentiate sodium pentobarbital sleeping time in albino mice.