Premium
Synthesis of 3‐aryl‐4‐oxothiazolin‐2‐yl(4‐ethoxy‐3‐methoxy)phenyl hydrazones as possible anticonvulsants
Author(s) -
Dimri A. K.,
Parmar S. S.
Publication year - 1978
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570150235
Subject(s) - chemistry , alkoxy group , aryl , medicinal chemistry , organic chemistry , alkyl
Several 3‐aryl‐4‐oxo‐thiazolin‐2‐yl(4‐ethoxy‐3‐methoxy)phenyl hydrazones were synthesized and evaluated for their anticonvulsant activity. Three of these substituted hydrazones provided 80% protection against pentylenetetrazol‐induced convulsions in mice.