Premium
Substituted 2,3‐dihydro‐4(1 H )quinazoIinones, 2
Author(s) -
Yale Harry L.
Publication year - 1977
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570140812
Subject(s) - chemistry , aryl , alkyl , primary (astronomy) , organic chemistry , combinatorial chemistry , medicinal chemistry , physics , astronomy
Details are given for the reaction of isatoic anhydrides with different primary aromatic amines to give several new N ‐aryl‐ o ‐aminobenzamides. The latter were annulated with a variety of dialkyl and alkyl aryl ketones to give 2,3‐dihydro‐4(1 H )quinazolinones. Several novel and efficient procedures for effecting the cyclization are described.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom