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Synthesis of 2‐amino‐3‐carbethoxy‐1‐hydroxyindoles
Author(s) -
Munshi K. L.,
Kohl H.,
De Souza N. J.
Publication year - 1977
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570140704
Subject(s) - chemistry , stereochemistry , medicinal chemistry , combinatorial chemistry
A general method is described for the synthesis of 2‐amino‐3‐carbethoxy‐l‐hydroxyindoles by the reductive cyclization of 2‐nitrophenylcyanoacetates using zinc and acetic acid at temperatures of 15–28°.
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