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Synthesis of 1‐amino‐5‐phenyl‐4,5‐dihydro‐3 H ‐2‐benzazepines and the isomeric 2‐amino‐1‐benzazepines
Author(s) -
Kukla Michael J.
Publication year - 1977
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570140543
Subject(s) - benzazepines , chemistry , stereochemistry , ether , lactam , medicinal chemistry , organic chemistry
The title amidines (1 and 2) were synthesized. A synthesis of lactam 10 free of isomeric 4 is described. An interesting rate difference in displacement of thiomethyl ether intermediates 5 and 11 with amines was observed.
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