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2‐Aminothiazole derivatives. I. Mass spectra of 2‐acetylacetamidothiazoles and N ‐(2‐thiazolyl)‐β‐(2′‐thiazolylamino)crotonamides
Author(s) -
SaintRuf G.,
Silou Th.
Publication year - 1977
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570140530
Subject(s) - chemistry , fragmentation (computing) , mass spectrum , ion , electron ionization , computational chemistry , electron transfer , medicinal chemistry , stereochemistry , organic chemistry , ionization , operating system , computer science
2‐Acetylacetamidothiazoles ( 2 ) and N ‐(2‐thiazolyl)‐β‐(2′‐thiazolylamino)crotonamides ( 3 ) break down in a well‐defined manner upon electron impact. In either of the two cases, the fragmentation pattern involves hydrogen transfer, similar to the McLafferty rearrangement. The principal ions formed are characterised and the most plausible mechanism of their formation is discussed.