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Benzo[ f ]isoindole analogs II. Thieno[3,4‐ b ]quinoxaline
Author(s) -
Roland Mitchel M.,
Anderson Richard C.
Publication year - 1977
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570140402
Subject(s) - quinoxaline , chemistry , isoindole , dimethyl acetylenedicarboxylate , dehydration , dehydrogenation , medicinal chemistry , stereochemistry , organic chemistry , cycloaddition , catalysis , biochemistry
The transient existence of thieno[3,4‐ b ]quinoxaline ( 2d ) as a product of dehydration of 1,3‐dihydrothieno[3,4‐ b ]quinoxaline 2‐oxide ( 5 ) was demonstrated by trapping experiments with N ‐phenylmaleimide and dimethyl acetylenedicarboxylate. Attempts to isolate 2d from reaction mixtures arising from dehydration of 5 and from dehydrogenation of 1,3‐dihydro‐thieno[3,4‐ b ]quinoxaline ( 8 ) were unsuccessful.