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Oxindoles from α‐acyloxyamides
Author(s) -
Barker Marvin W.,
Sung HsiuSun
Publication year - 1977
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570140336
Subject(s) - chemistry , carbonium ion , boron trifluoride , electrophile , hydrolysis , ring (chemistry) , medicinal chemistry , organic chemistry , boron , ion , catalysis
Oxindoies have been obtained in good yields from the reaction of several a‐acyloxy‐α,α‐diphenylacetanilides and boron trifluoride etherate. The reaction probably occurs by hydrolysis of the ester followed by electrophilic substitution of the resultant carbonium ion on the anilide ring.