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The reaction of β‐aminoaleohols with o ‐Phthalaldehyde
Author(s) -
Shipchandler M. T.
Publication year - 1977
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570140227
Subject(s) - chemistry , o phthalaldehyde , ring (chemistry) , medicinal chemistry , organic chemistry , derivatization , high performance liquid chromatography
The reaction of o ‐phthalaldehyde with β‐aminomonohydroxy compounds leads to ortho ‐substituled phenyloxazolines. β‐Aminodiols or‐triols give tetracyelic bisoxazoiidines when reacted with o ‐phthalaldchyde. These two type of ring systems are generated in one step under extremely mild conditions.