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3‐Halo‐4‐imino‐2‐azetidinones via acykchloroformamidines
Author(s) -
Brady William T.,
Owens Robert A.
Publication year - 1977
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570140141
Subject(s) - chemistry , yield (engineering) , halide , halo , combinatorial chemistry , medicinal chemistry , organic chemistry , thermodynamics , physics , quantum mechanics , galaxy
α‐Haloacid Halides react with carbodimides to yield acylchloroformamidines which upon treatment with trithylamine undergo conversion to 3‐halo4‐imino‐2‐azetidinones in good yiels. Two pathways are possible for this conversion and these are discussed.