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Synthesis of 3,3′ ‐methylenediisoxazoles
Author(s) -
Auricchio S.,
Ricca A.,
De Pava O. Vajna
Publication year - 1977
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570140133
Subject(s) - chemistry , chlorine , ether , medicinal chemistry , transformation (genetics) , chlorine atom , organic chemistry , biochemistry , gene
The synthesis of new 3,3′‐methylenediisoxazoles (III), from 1,3‐dichloromalondioxime (IX) and acetylenic compounds is reported. We have studied the transformation of the chloronitroso compound (VII), obtained from malondioxime (V) in ether with gaseous chlorine at −70°, into IX. It was found that this was possible only by heating a DIYISO solution. The characteristics of the compounds which are described are reported.